Time regions specify the color and tooltip for particulars interval of time in scheduler. Regions are specified for days, time of day, resources or for any combination of ones. In this example they indicate a lunch in green color or a coffee break (second day only) in red color. Notice, there are tooltips describing reason as well. The coffee break is created in code.

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If you would look into a source code for this demo, click on the link.
For demonstration purposes all appointments displayed on a calendar are stored in ASP.NET session objects, so original values are restored immediately after a new session object is created.
A list of appointments and resources is intialized every time a new session is started.